Marie Muller

Associate Professor

Dr. Muller is interested in medical ultrasound and ultrasound propagation in complex media.  Her long-term objective is to advance the state-of-the-art of medical ultrasound and contribute to screening and prevention methods.

Her  research attracts students because of its high societal impact, because it involves both theory and the learning about state-of-the-art numerical and experimental methods, and because it involves teamwork and collaborations with physicians, physicists and engineers. Since her research is multidisciplinary, students in her lab have the opportunity to tailor their graduate experience to their particular interests. Her applications involve developing non-invasive methods to quantitatively characterize the microstructure of complex biological media such as lung and bone. This leads to the development of new technologies for the diagnosis and monitoring of osteoporosis, pulmonary fibrosis, and pulmonary edema.

Outside of work, she enjoys family, friends, music and food.

Publications

Design Optimization and Tradeoff Analysis of an Actuated Continuum Probe for Pulmonary Nodule Localization and Resection
Mccullough, M. D., Muller, M., Egan, T. M., & Buckner, G. D. (2024), BIOENGINEERING-BASEL, 11(5). https://doi.org/10.3390/bioengineering11050417
High-Performance PMN-PT Single-Crystal-Based 1-3 Composite Transducer Integrated with a Biopsy Needle
Kreager, B. C., Wu, H., Chang, W.-Y., Moon, S., Mitchell, J., Peng, C., … Jiang, X. (2024), BIOSENSORS-BASEL, 14(2). https://doi.org/10.3390/bios14020074
Lung quantitative ultrasound to stage and monitor interstitial lung diseases
Dashti, A., Roshankhah, R., Lye, T., Blackwell, J., Montgomery, S., Egan, T., … Muller, M. (2024), SCIENTIFIC REPORTS, 14(1). https://doi.org/10.1038/s41598-024-66390-6
The respective and dependent effects of scattering and bone matrix absorption on ultrasound attenuation in cortical bone
McCandless, B. A., Raum, K., & Muller, M. (2024), PHYSICS IN MEDICINE AND BIOLOGY, 69(11). https://doi.org/10.1088/1361-6560/ad3fff
Investigating pulmonary edema in rat lungs using separation of multiple scattering and single scattering contribution
Roshankhah, R., Blackwell, J., Yuan, H., Egan, T. M., & Muller, M. (2023, March), JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, Vol. 153. https://doi.org/10.1121/10.0018614
Lung nodule biopsy guided using a 30 MHz ultrasound transducer: in vitro study
Kreager, B., Moon, S., Mitchell, J., Wu, H., Peng, C., Muller, M., … Jiang, X. (2023), (P. Fromme & Z. Su, Eds.). https://doi.org/10.1117/12.2658585
Random matrix theory (RMT) to quantify scattering behavior in lung mimicking phantoms
Dong, Z., Cole, A. D., Onuorah, C. W., Ware, H. O., & Muller, M. (2023, March), JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, Vol. 153. https://doi.org/10.1121/10.0018611
Random matrix theory to quantify micro-structural changes in rodent lungs due to pulmonary diseases
Cole, A. D., Roshankhah, R., Blackwell, J., Montgomery, S. A., Egan, T. M., & Muller, M. (2023, March), JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, Vol. 153. https://doi.org/10.1121/10.0018613
Ultrasound Characterization of Cortical Bone Using Shannon Entropy
Karbalaeisadegh, Y., Yao, S., Zhu, Y., Grimal, Q., & Muller, M. (2023), ULTRASOUND IN MEDICINE AND BIOLOGY, 49(8), 1824–1829. https://doi.org/10.1016/j.ultrasmedbio.2023.04.006
Estimation of Thickness and Speed of Sound for Transverse Cortical Bone Imaging Using Phase Aberration Correction Methods: An In Silico and Ex Vivo Validation Study
Minh, H. N., Muller, M., & Raum, K. (2022), APPLIED SCIENCES-BASEL, 12(10). https://doi.org/10.3390/app12105283

View all publications via NC State Libraries

Grants

  • Quantitative Assessment of Angiogenesis using Ultrasound Multiple Scattering
  • Novel Ultrasonic Methods for the Assessment of Pulmonary Edema
  • Novel Ultrasound Localization of Pulmonary Nodules during Video Assisted Thoracic Surgery to Improve Surgical Resection
  • Innovative Ultrasonic Methods For The Diagnosis And Monitoring Of Pulmonary Fibrosis
  • Ultrasound Enhanced Platelet-like Particle Therapy for Accelerated Wound Repair
  • Ultrasonic Characterization of Atherosclerotic Plaque using Multiple Scattering
  • Assessment of Bone Micro-Structure using Ultrasonic Methods
  • Experimental Ultrasonic Characterization of Bone Micro-Architecture
  • Quantitative Characterization of Trabecular Bone Micro-Architecture Using Ultrasound Applications to the Diagnosis and Monitoring of Spaceflight Osteopenia
Marie Muller