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MAE Seminar: Marie Muller
September 6 @ 10:00 am - 11:00 am
Title:
“Quantitative ultrasound in complex tissues: finding new sources of contrast”
Abstract:
Highly heterogeneous tissues such as lungs or bone break the fundamental assumptions at the basis of conventional ultrasound imaging. Ultrasound signals that propagate in such media are too complex to form conventional images. However, this complexity is also a very rich source of information, since complex acoustic signatures are packed with information on tissue structure. Our objective is to extract quantitative information on tissue microstructure, by applying physics-based models of ultrasound scattering. We demonstrate that such approaches can be applied to the characterization and staging of lung diseases such as pulmonary fibrosis and edema, or of bone diseases such as osteoporosis. These chronic diseases require frequent monitoring. Developing non-invasive, non-ionizing and quantitative methods to evaluate the progression of such diseases is therefore critical. We also show that novel imaging methods for lung cancer using multiple scattering as a source of contrast holds great promise for the real-time guiding of lung cancer surgery.
Bio:
Marie Muller is an Associate Professor in Mechanical and Aerospace Engineering at North Carolina State University. She received her B.S. in Physics from the Pierre et Marie Curie University in Paris, France in 2002, and her Ph.D in Physical Acoustics from the University of Paris, France in 2006. After a postdoctorate at the Erasmus Medical Center in Rotterdam, the Netherlands, she returned to Paris, as an Assistant Professor with the Institut Langevin. In 2014, she joined the Mechanical and Aerospace Engineering department at NCSU. She is also an associate Faculty with the Joint Department of Biomedical Engineering at UNC and NCSU.
Dr. Muller’s work has been recognized with several awards, including the Galien Medstartup Award in 2020, the ICU Early Career Award, the Young Investigator Award from the French Society of Acoustics. She is a member of IEEE, the Acoustical Society of America, and of the American Institute of Ultrasound in Medicine. She is also a founding member and member of the board of the International Bone Ultrasound Society.”
